Intro to Cancer and disruption of cell cycle control

I passed back the worksheet from Chapter 12.

We discussed what is going to be on tomorrow's test:

• All of Chapter 7 - membrane structure, transport (including water potential)
• Cell communication from blog on 10/
• Ch. 12.1 and 12.2 - cell cycle and mitosis, including cytokinesis adn binary fission
• Cancer as a disruption of cell cycle controls - roles of protooncogenes and tumor suppressor genes

We then read the beginning of the Cell Biology and Cancer packet and discussed what cancer is.  The focus questions for this reading were:

1. What is the normal role of a proto-oncogene?
2. What is the normal role of a tumor suppressor gene?
3. Why must there be mutations to both tumor suppressor genes and proto-oncogenes for cancer to occur?
4. Would you need mutations in both copies of your proto-oncogenes to cause a problem to the cell cycle?  Explain.
5. Would you need mutations in both copies of your tumor suppressor genes to cause a problem to the cell cycle?  Explain.

Your homework is to study for tomorrow's test!